BDBM384095 US10280167, Example 24

SMILES Nc1nc(nc2n(Cc3ccc4CCNCc4c3)c(=O)[nH]c12)-c1ncc[nH]1

InChI Key InChIKey=QONHJLATERGMLT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384095   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM384095(US10280167, Example 24)
Affinity DataEC50:  46nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent