BDBM384561 6-chloro-N-[trans-4- (morpholin-4- yl)cyclohexyl]quinazolin- 4-amine::US9932350, 2-13

SMILES Clc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1

InChI Key InChIKey=PEBXDAAUGYCVMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384561   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384561(US9932350, 2-13 | 6-chloro-N-[trans-4- (morpholin-...)
Affinity DataIC50: 6nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent