BDBM385722 2-fluoro-4-(7-{[(3- methyloxetan-3- yl)methyl]amino}- [1,2,4]triazolo[1,5- a]pyridin-5- yl)benzonitrile::US10287286, Example 127

SMILES CC1(CNc2cc(-c3ccc(C#N)c(F)c3)n3ncnc3c2)COC1

InChI Key InChIKey=RXMYAFFQPTUGQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385722   

TargetProlyl hydroxylase EGLN2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM385722(2-fluoro-4-(7-{[(3- methyloxetan-3- yl)methyl]amin...)
Affinity DataIC50: 47nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
US Patent