BDBM386092 (2S,4R)-1-(2-(3- acetyl-5-(1-acetyl- 1,2,3,6- tetrahydropyridin- 4-yl)-1H-indol-1- yl)acetyl)-N-(2'- chloro-2- fluorobiphenyl-3- yl)-4- fluoropyrrolidine-2- carboxamide::US10287301, Compound 28::US10822352, Comp No. 28

SMILES CC(=O)N1CCC(=CC1)c1ccc2n(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(c3F)-c3ccccc3Cl)cc(C(C)=O)c2c1

InChI Key InChIKey=JCMJPXPJGAFUHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 386092   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386092((2S,4R)-1-(2-(3- acetyl-5-(1-acetyl- 1,2,3,6- tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386092((2S,4R)-1-(2-(3- acetyl-5-(1-acetyl- 1,2,3,6- tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
Go to US Patent