BDBM386727 US10287301, Compound 679::US10822352, Comp No. 679::methyl 2-(6- ((2S,4R)-1-(2-(3- acetyl-5-(2- methylpyrazolo[1,5- a]pyrimidin-6- yl)-1H-indazol-1- yl)acetyl)-4- fluoropyrrolidine- 2-carboxamido) pyridin-2-yl)acetate

SMILES COC(=O)Cc1cccc(NC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Cn2nc(C(C)=O)c3cc(ccc23)-c2cnc3cc(C)nn3c2)n1

InChI Key InChIKey=GKZHWMNYXBTBSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 386727   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386727(methyl 2-(6- ((2S,4R)-1-(2-(3- acetyl-5-(2- methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386727(methyl 2-(6- ((2S,4R)-1-(2-(3- acetyl-5-(2- methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent