BDBM387169 1-(5-((5-chloro-2-((1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)amino)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethanone::US9938257, Example 1

SMILES CC(=O)N1CC2CC(CC2C1)Nc1nc(Nc2cnn(CC(C)(C)O)c2)ncc1Cl

InChI Key InChIKey=JVGHAGIBZTYWHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387169   

TargetTyrosine-protein kinase JAK1(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387169(1-(5-((5-chloro-2-((1-(2-hydroxy-2-methylpropyl)-1...)
Affinity DataIC50: 10nMAssay Description:JAK1:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetAurora kinase A(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387169(1-(5-((5-chloro-2-((1-(2-hydroxy-2-methylpropyl)-1...)
Affinity DataIC50: 58nMAssay Description:Aurora-A:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent