BDBM387183 N4-(2-(tert-butylsulfonyl)octahydrocyclopenta[c]pyrrol-5-yl)-5-chloro-N2-(1-methyl-1H-pyrazol-4-yl)pyrimidine-2,4-diamine::US9938257, Example 31

SMILES Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(CC4C3)S(=O)(=O)C(C)(C)C)n2)cn1

InChI Key InChIKey=HUEYRDISNSWJHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387183   

TargetAurora kinase A(Human)
Calitor Sciences

US Patent
LigandPNGBDBM387183(N4-(2-(tert-butylsulfonyl)octahydrocyclopenta[c]py...)
Affinity DataIC50: 50nMAssay Description:Aurora-A:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent