BDBM387262 N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-yl)-2′-methoxy- [1,1′-biphenyl]-4-yl)- 4-methyl-1,2,3- thiadiazole-5- carboxamide::US10292981, Example 16

SMILES COc1ccc(cc1-c1ccc(NC(=O)c2snnc2C)cc1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=LMRKQWYLNWUYRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387262   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387262(US10292981, Example 16 | N-(5′- (5,5-Dimethy...)
Affinity DataIC50: 100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent