BDBM387271 2,6- Difluoro-N-(5-(2- methoxy-5-(4- methyl-5-oxo-4,5- dihydro-1,3,4- oxadiazol-2- yl)phenyl)pyrazin- 2-yl)benzamide::US10292981, Example 93

SMILES COc1ccc(cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1)-c1nn(C)c(=O)o1

InChI Key InChIKey=WBHMQSQHURVXPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387271   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387271(US10292981, Example 93 | 2,6- Difluoro-N-(5-(2- me...)
Affinity DataIC50: 100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent