BDBM387276 5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-yl)-2-ethylphenyl)- N-(3-methylpyridin- 4-yl)thiophene-2- carboxamide ::US10292981, Example 158

SMILES CCc1ccc(cc1-c1ccc(s1)C(=O)Nc1ccncc1C)C1=NOC(C)(C)C1=O

InChI Key InChIKey=BPEWWUFHHJJALF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387276   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387276(US10292981, Example 158 | 5-(5- (5,5-Dimethyl-4-ox...)
Affinity DataIC50: 100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent