BDBM387284 N-(2′- chloro-5′-(5,5- dimethyl-4-oxo-4,5- dihydroisoxazol-3- yl)-[1,1′-biphenyl]-4- yl)-2,6- difluorobenzamide::US10292981, Example 11

SMILES CC1(C)ON=C(C1=O)c1ccc(Cl)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1

InChI Key InChIKey=VPNVXPWEPKFNHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387284   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387284(US10292981, Example 11 | N-(2′- chloro-5R...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent