BDBM387285 N-(6-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-yl)-2- methoxyphenyl)pyridin- 3-yl)-2,6- difluorobenzamide::US10292981, Example 18

SMILES COc1ccc(cc1-c1ccc(NC(=O)c2c(F)cccc2F)cn1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=DZMUSTHWHKLETA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387285   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387285(US10292981, Example 18 | N-(6-(5- (5,5-dimethyl-4-...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent