BDBM387287 2,6- Difluoro-N-(5′-(4- methoxy-5,5- dimethyl-4,5- dihydroisoxazol-3- yl)-2′-methyl-[1,1′- biphenyl]-4- yl)benzamide::US10292981, Example 24

SMILES COC1C(=NOC1(C)C)c1ccc(C)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1

InChI Key InChIKey=OVAPXSYEFRBAPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387287   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387287(US10292981, Example 24 | 2,6- Difluoro-N-(5′...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent