BDBM387295 3,5- Dichloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- dihydroisoxazol-3- yl)-2- methylphenyl)pyrazin- 2-yl)isonicotinamide::US10292981, Example 103

SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2c(Cl)cncc2Cl)cn1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=HLZWGPWIRVRBGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387295   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387295(US10292981, Example 103 | 3,5- Dichloro-N-(5-(5-(5...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent