BDBM387306 US10292981, Example 136

SMILES CN(C)c1ccc(cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=SUODEOOJCNLTFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387306   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387306(US10292981, Example 136)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent