BDBM388226 US10294229, Example 375

SMILES CC(C)(O)CCc1cn(nn1)-c1cnc(cc1N[C@@H]1CCC[C@@H]1F)-n1ncc2cc(cnc12)C#N

InChI Key InChIKey=NMOSEHMHSMKNCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388226   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM388226(US10294229, Example 375)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent