BDBM388497 US9944618, Compound ID No. 31

SMILES CNC[C@@H]([C@H](OCc1cccn(C)c1=O)c1ccccc1)c1ccc2ccccc2c1

InChI Key InChIKey=VSNUOCFDBKBETJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 388497   

TargetSodium-dependent serotonin transporter(Human)
Mayo Foundation

US Patent
LigandPNGBDBM388497(US9944618, Compound ID No. 31)
Affinity DataKi:  1.90nMAssay Description:SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Mayo Foundation

US Patent
LigandPNGBDBM388497(US9944618, Compound ID No. 31)
Affinity DataKi:  2.40nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Human)
Mayo Foundation

US Patent
LigandPNGBDBM388497(US9944618, Compound ID No. 31)
Affinity DataKi:  24.6nMAssay Description:DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent