BDBM389004 4-[5-[4-(dimethylamino)piperidin-1- yl]-8-(5-fluoro-6-methylpyridin-3- yl)imidazo[1,2-c]pyrimidin-7- yl]benzonitrile 1H NMR (500 MHz, CD3OD) $#948; 8.14 (m, 2H), 7.95 (d, J = 2.0 Hz, 1H), 7.73-7.67 (m, 3H), 7.64- 7.58 (m, 2H), 4.37 (d, J = 13.7 Hz, 2H), 3.61 (m, 1H), 3.39-3.31 (m, 2H), 2.95 (s, 6H), 2.57 (d, J = 2.8 Hz, 3H), 2.29 (d, J = 11.1 Hz, 2H), 2.09 (m, 2H).::US10800779, Example 113::US11401272, Example 113::US9944647, Example 113
SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(F)c2)c2nccn12
InChI Key InChIKey=AASTYTWNCKDYFE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 389004
Affinity DataIC50: 50nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair