BDBM389160 US9951026, 3-3

SMILES OC(=O)c1ccc(cc1)C(=C\c1cn(Cc2ccc(F)cc2)c2nc(Cl)ccc12)\C#N

InChI Key InChIKey=BFOUYOFHFVRNQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389160   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM389160(US9951026, 3-3)
Affinity DataIC50: 5.03E+4nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent