BDBM390034 4-amino-1-[[1-[(E)-4- (dimethylamino)but-2- enoyl]azetidin-3-yl]methyl]-3-(4- phenoxyphenyl)-6H-pyrrolo[2,3- d]pyridazin-7-one::US10323037, Example 47::US9951077, 47

SMILES CN(C)C\C=C\C(=O)N1CC(Cn2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c(=O)c23)C1

InChI Key InChIKey=VYRUICCRBCHNCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390034   

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390034(4-amino-1-[[1-[(E)-4- (dimethylamino)but-2- enoyl]...)
Affinity DataIC50: 10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390034(4-amino-1-[[1-[(E)-4- (dimethylamino)but-2- enoyl]...)
Affinity DataIC50: 10nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent