BDBM390714 6-Amino-N-(3-chlorophenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide::US9957261, Example 70

SMILES NC1CCc2cc(ccc2C1)C(=O)Nc1ccc(cc1)C#N

InChI Key InChIKey=AHANBGIKULJGRA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390714   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390714(US9957261, Example 70 | 6-Amino-N-(3-chlorophenyl)...)
Affinity DataKi:  3.20nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390714(US9957261, Example 70 | 6-Amino-N-(3-chlorophenyl)...)
Affinity DataKi:  4.40nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent