BDBM390735 (R)-N-(3-Aminochroman-7-yl)-2,6-dichloroisonicotinamide::US9957261, Example 91

SMILES N[C@H]1COc2cc(NC(=O)c3cc(Cl)nc(Cl)c3)ccc2C1

InChI Key InChIKey=PDZXJRMYJYEBSY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390735   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390735(US9957261, Example 91 | (R)-N-(3-Aminochroman-7-yl...)
Affinity DataKi:  3.5nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390735(US9957261, Example 91 | (R)-N-(3-Aminochroman-7-yl...)
Affinity DataKi:  7.70nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent