BDBM39091 MLS000036929::SMR000041329::[4-amino-2-(isopropylamino)thiazol-5-yl]-(3-methoxyphenyl)methanone::[4-amino-2-(propan-2-ylamino)-1,3-thiazol-5-yl]-(3-methoxyphenyl)methanone::[4-amino-2-(propan-2-ylamino)-5-thiazolyl]-(3-methoxyphenyl)methanone::[4-azanyl-2-(propan-2-ylamino)-1,3-thiazol-5-yl]-(3-methoxyphenyl)methanone::cid_660516

SMILES COc1cccc(c1)C(=O)c1sc(NC(C)C)nc1N

InChI Key InChIKey=UMWFADAYTHDOHK-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39091   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39091(MLS000036929 | [4-azanyl-2-(propan-2-ylamino)-1,3-...)
Affinity DataEC50:  330nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39091(MLS000036929 | [4-azanyl-2-(propan-2-ylamino)-1,3-...)
Affinity DataIC50: 4.94E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39091(MLS000036929 | [4-azanyl-2-(propan-2-ylamino)-1,3-...)
Affinity DataIC50: 5.26E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39091(MLS000036929 | [4-azanyl-2-(propan-2-ylamino)-1,3-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay