BDBM391730 4-(4-((1,2,4-Thiadiazol-5-yl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-2-(trifluoromethyl)benzonitrile::US10300067, Example 1

SMILES FC(F)(F)c1cc(ccc1C#N)N1CCc2c(C1)ncnc2Nc1ncns1

InChI Key InChIKey=DFIKGMDEVWTTTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391730   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391730(US10300067, Example 1 | 4-(4-((1,2,4-Thiadiazol-5-...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent