BDBM391748 4-(4-((4-Isopropoxyphenyl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-2-(trifluoromethyl)benzonitrile::US10300067, Example 2

SMILES CC(C)Oc1ccc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(c2)C(F)(F)F)cc1

InChI Key InChIKey=NFICWXIZQMUWRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391748   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391748(US10300067, Example 2 | 4-(4-((4-Isopropoxyphenyl)...)
Affinity DataIC50: 370nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent