BDBM391766 4-(4-((4-(3-(4-(Methylsulfonyl)piperazin-1-yl)propoxy)phenyl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-2-(trifluoromethyl)benzonitrile::US10300067, Example 18

SMILES CS(=O)(=O)N1CCN(CCCOc2ccc(Nc3ncnc4CN(CCc34)c3ccc(C#N)c(c3)C(F)(F)F)cc2)CC1

InChI Key InChIKey=AHSDXYVBJZPEEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391766   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391766(US10300067, Example 18 | 4-(4-((4-(3-(4-(Methylsul...)
Affinity DataIC50: 360nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent