BDBM391767 6-((7-(4-Cyano-3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-N-cyclopropylpyridine-3-sulfonamide::US10300067, Example 19

SMILES FC(F)(F)c1cc(ccc1C#N)N1CCc2c(C1)ncnc2Nc1ccc(cn1)S(=O)(=O)NC1CC1

InChI Key InChIKey=PRMLYRHGWRPCRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391767   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391767(US10300067, Example 19 | 6-((7-(4-Cyano-3-(trifluo...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent