BDBM391782 5-((7-(4-Cano-3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-N-(2-(1-methyl-1H-pyrazol-5-yl)ethyl)-1,3,4-thiadiazol-2-carboxamide::US10300067, Example 35

SMILES Cn1nccc1CCNC(=O)c1nnc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(c2)C(F)(F)F)s1

InChI Key InChIKey=JHNFHZMBYMZYOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391782   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391782(US10300067, Example 35 | 5-((7-(4-Cano-3-(trifluor...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
Entry Details
US Patent