BDBM391783 6-((7-(4-Cano-3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-N-((4-(trifluoromethyl)thiazol-2-yl)methyl)nicotinamide::US10300067, Example 36

SMILES FC(F)(F)c1csc(CNC(=O)c2ccc(Nc3ncnc4CN(CCc34)c3ccc(C#N)c(c3)C(F)(F)F)nc2)n1

InChI Key InChIKey=YGBIUCWZPMCAAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391783   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391783(US10300067, Example 36 | 6-((7-(4-Cano-3-(trifluor...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
Entry Details
US Patent