BDBM391784 (R)—N-(1-(1,3,4-Oxadiazol-2-yl)ethyl)-2-((7-(4-cyano-3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)amino)-4-(trifluoromethyl) thiazol-5-carboxamide::US10300067, Example 37

SMILES C[C@@H](NC(=O)c1sc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(c2)C(F)(F)F)nc1C(F)(F)F)c1nnco1

InChI Key InChIKey=PJFNLAKFLIHXIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391784   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391784(US10300067, Example 37 | (R)—N-(1-(1,3,4-Oxad...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent