BDBM391792 2-Bromo-4-(4-((5-(2-hydroxypropan-2-yl)pyridin-2-yl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)benzonitrile::US10300067, Example 44

SMILES CC(C)(O)c1ccc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(Br)c2)nc1

InChI Key InChIKey=NLQASHOSGYSOCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391792   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391792(US10300067, Example 44 | 2-Bromo-4-(4-((5-(2-hydro...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent