BDBM391803 2-Chloro-4-(4-((6-fluoro-5-(1-hydroxycyclobutyl)pyridin-2-yl)amino)-5,6-dihydropyrido[3,4-d]pyrimidin-7 (8H)-yl)benzonitrile::US10300067, Example 56

SMILES OC1(CCC1)c1ccc(Nc2ncnc3CN(CCc23)c2ccc(C#N)c(Cl)c2)nc1F

InChI Key InChIKey=JBQHPBPRUVLCDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391803   

TargetAndrogen receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM391803(US10300067, Example 56 | 2-Chloro-4-(4-((6-fluoro-...)
Affinity DataIC50: 840nMAssay Description:Antagonist activity for AR was evaluated according to the following method. COS-7 cells (ATCC) were transfected with pMMTV-luc vector (reporter plasm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent