BDBM391899 N-((1-(4- (methylsulfonyl) benzyl)piperidin-4- yl)methyl)-2'',3''- dihydrospiro [cyclopropane- 1,1''-inden]- 2-amine::US10301253, Example 50::US10301253, Example 51
SMILES CS(=O)(=O)c1ccc(CN2CCC(CNC3CC33CCc4ccccc34)CC2)cc1
InChI Key InChIKey=RTOCOXHEZYQSAH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 391899
Affinity DataIC50: 50nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
Affinity DataIC50: 47.4nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
Affinity DataIC50: 64.7nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair