BDBM391901 Boc Deprotection::US10301253, Example 52

SMILES C(NC1CC11CCCc2ccccc12)C1CCNCC1

InChI Key InChIKey=QPPMDZRAAPQDAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391901   

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391901(US10301253, Example 52 | Boc Deprotection)
Affinity DataIC50: 81.8nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391901(US10301253, Example 52 | Boc Deprotection)
Affinity DataIC50: 65.4nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent