BDBM391921 6'-methyl-N-(piperidin-4- ylmethyl)-2',3'- dihydrospiro[cyclopropane- 1,1'-inden]-2-amine::US10301253, Example 72

SMILES Cc1ccc2CCC3(CC3NCC3CCNCC3)c2c1

InChI Key InChIKey=IKUSGUZXHPUQAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391921   

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391921(US10301253, Example 72 | 6'-methyl-N-(piperidin-4-...)
Affinity DataIC50: 34.4nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391921(US10301253, Example 72 | 6'-methyl-N-(piperidin-4-...)
Affinity DataIC50: 36.4nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent