BDBM392071 3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)pyrazin-2-yl)thio)-4-chlorophenol::US10301278, Example 9

SMILES CC1(N)CCN(CC1)c1cnc(Sc2cc(O)ccc2Cl)c(N)n1

InChI Key InChIKey=MXULSJHLEIEILR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392071   

LigandPNGBDBM392071(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)pyra...)
Affinity DataIC50: 307nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent