BDBM392317 5-amino-3-(4-(aminomethyl)-4-(pyridin-2-yl)piperidin-1-yl)-6-((2-(trifluoromethyl)pyridin-3-yl)thio)pyrazine-2-carboxamide::US10301278, Example 34
SMILES NCC1(CCN(CC1)c1nc(N)c(Sc2cccnc2C(F)(F)F)nc1C(N)=O)c1ccccn1
InChI Key InChIKey=QGLJMTRJXNGMFB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 392317
Affinity DataIC50: 102nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
