BDBM392729 Example 29::US10301291, Compound 14e

SMILES Clc1ccc(cc1Cl)-c1ncc(CC#N)n1-c1ccnc(NC2CCCNC2)n1

InChI Key InChIKey=KDDPNNXAZURUGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392729   

TargetMitogen-activated protein kinase 10(Human)
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392729(Example 29 | US10301291, Compound 14e)
Affinity DataIC50: 65nMAssay Description:First of all, after a substrate was inserted into a prepared base reaction buffer solution (20 mM Hepes (pH 75), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent