BDBM392810 N-(4-(1-(2-Fluoro-4-(trifluoromethyl)benzyl)-3-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl)cyclopropanecarboxamide::US10301306, Example 8

SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccc(cc2F)C(F)(F)F)c1-c1ccnc(NC(=O)C2CC2)c1

InChI Key InChIKey=YGYRGXLKSGCCDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392810   

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM392810(N-(4-(1-(2-Fluoro-4-(trifluoromethyl)benzyl)-3-(4-...)
Affinity DataIC50: 30nMAssay Description:The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2020
Entry Details
US Patent