BDBM393006 7-(4-((1 S,4S)-2-oxa-5-azabicyclo[2.2.1]heptane-5-ylmethyl)benzyl)-2-butoxy-5H-pyrrolo[3,2-d]pyrimidine-4-amine::US9962388, Compound Example 18

SMILES CCCCOc1nc(N)c2[nH]cc(Cc3ccc(CN4C[C@@H]5C[C@H]4CO5)cc3)c2n1

InChI Key InChIKey=LHDRQMCZIVOLBH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393006   

TargetToll-like receptor 7(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM393006(US9962388, Compound Example 18 | 7-(4-((1 S,4S)-2-...)
Affinity DataEC50:  5.5nMAssay Description:Reagents:HEK-blue hTLR7 cell and HEK-blue hTLR8 cell (available from InvivoGen)DMEM mediumheat inactivated fetal bovine serumAnti Mycoplasma reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent