BDBM393038 4-amino-2-butoxy-7-(4-((4-methylpiperazine-1-yl)methyl)benzyl)-5H-pyrrolo[3,2-d]pyrimidine-6-carbonitrile::US9962388, Compound Example 44

SMILES CCCCOc1nc(N)c2[nH]c(C#N)c(Cc3ccc(CN4CCN(C)CC4)cc3)c2n1

InChI Key InChIKey=TZAYCQZJLPYLCB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393038   

TargetToll-like receptor 7(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM393038(US9962388, Compound Example 44 | 4-amino-2-butoxy-...)
Affinity DataEC50:  0.5nMAssay Description:Reagents:HEK-blue hTLR7 cell and HEK-blue hTLR8 cell (available from InvivoGen)DMEM mediumheat inactivated fetal bovine serumAnti Mycoplasma reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent