BDBM3932 4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}morpholine::5-Substituted 1-Phenylbenzimidazole 21::5-[4-(4-Morpholino)butoxy]-1]phenylbenzimidazole Dihydrochloride

SMILES C(CCN1CCOCC1)COc1ccc2n(cnc2c1)-c1ccccc1

InChI Key InChIKey=MMCPIFMHHYLZBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3932   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM3932(4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM3932(4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...)
Affinity DataIC50: 1.20E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM3932(4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...)
Affinity DataIC50: 2.50E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed