BDBM393339 5-(3-Fluoro-4-methoxyphenyl)-2-(((1R,3R)-3-isothiocyanatocyclobutoxy)methyl)pyridine::US9963444, Example 42

SMILES COc1ccc(cc1F)-c1ccc(COC2C[C@@H](C2)N=C=S)nc1

InChI Key InChIKey=GAVRQMDMBSIEDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393339   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393339(US9963444, Example 42 | 5-(3-Fluoro-4-methoxypheny...)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent