BDBM393417 N-[5-[(2S,5R,6S)-5-amino-6- fluoro-oxepan-2-yl]-1-methyl- pyrazol-4-yl]-2-(2-fluoro-6- hydroxy-phenyl)thiazole-4- carboxamide::US9963446, Example 102

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2c(O)cccc2F)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=IAJKHASECAMBKL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393417   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM393417(US9963446, Example 102 | N-[5-[(2S,5R,6S)-5-amino-...)
Affinity DataKi:  0.121nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent