BDBM393440 N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1H-pyrazol- 4-yl)-2-(3-methylpyridin-2- yl)thiazole-4-carboxamide::US9963446, Example 128

SMILES Cc1cccnc1-c1nc(cs1)C(=O)Nc1cn[nH]c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=XHIMTRQOZBMLJT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393440   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM393440(US9963446, Example 128 | N-(5-((2S,5R,6S)-5-amino-...)
Affinity DataKi:  0.777nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent