BDBM393527 US9969687, Compound 191

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)c2C(=O)N(Cc3ccccn3)C(=O)c12

InChI Key InChIKey=DHLYQHPYVBLUGG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393527   

TargetC-C chemokine receptor type 9(Human)
Norgine

Curated by ChEMBL
LigandPNGBDBM393527(US9969687, Compound 191)
Affinity DataKi:  20nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 9(Human)
Norgine

Curated by ChEMBL
LigandPNGBDBM393527(US9969687, Compound 191)
Affinity DataKi:  33nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent