BDBM394056 5-[4-({trans-4-[(2R,6S)- 2,6-dimethylmorpholin-4- yl]cyclohexyl}amino) quinazolin-6-yl]pyridin-3-ol::US9969749, Example 5-6

SMILES C[C@H]1CN(C[C@@H](C)O1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)-c1cncc(O)c1

InChI Key InChIKey=FDWHJXSRFRXWAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394056   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394056(US9969749, Example 5-6 | 5-[4-({trans-4-[(2R,6S)- ...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
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