BDBM394122 US9975861, 2

SMILES CNC1=NC(NC(=O)N1)c1ccccc1C

InChI Key InChIKey=PAYYAYYJBDDZQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394122   

TargetGlycogen synthase kinase-3 beta(Human)
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394122(US9975861, 2)
Affinity DataIC50: 4.07E+4nMAssay Description:Human recombinant GSK-3β was purchased from Millipore (Millipore Iberica S.A.U.) The prephosphorylated polypeptide substrate was purchased from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394122(US9975861, 2)
Affinity DataIC50: 5.03E+4nMAssay Description:β-secretase (BACE-1, Sigma-Aldrich) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (Methoxycoumari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent