BDBM394201 US9975876, 26::ethyl 2-{[3R,6R)-1-{[3-fluoro-2-(2H- 1,2,3-triazol-2-yl)phenyl]carbonyl}-6- methylpiperidin-3-yl]oxy}-4- methoxypyridine-3-carboxylate

SMILES CCOC(=O)c1c(OC)ccnc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1cccc(F)c1-n1nccn1

InChI Key InChIKey=FJGUKGGDGAHLID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394201   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394201(US9975876, 26 | ethyl 2-{[3R,6R)-1-{[3-fluoro-2-(2...)
Affinity DataIC50: 39.6nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394201(US9975876, 26 | ethyl 2-{[3R,6R)-1-{[3-fluoro-2-(2...)
Affinity DataIC50: 2.79E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent