BDBM394208 US9975876, 33::methyl 2-methoxy-6-{[(3R,6R)-6- methyl-1-{[2-(2H-tetrazol-2- yl)phenyl]carbonyl}piperidin-3- yl]oxy}bcnzoate

SMILES COC(=O)c1c(OC)cccc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1ncnn1

InChI Key InChIKey=HZRYNAMRGBLXJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394208   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394208(US9975876, 33 | methyl 2-methoxy-6-{[(3R,6R)-6- me...)
Affinity DataIC50: 202nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394208(US9975876, 33 | methyl 2-methoxy-6-{[(3R,6R)-6- me...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent